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Research & Development Cell

Ongoing Research Projects

 
S.No. Title of Project and Sanction Letter No Sponsor / Funding Agency Sanctioned Amount (Rs. in Lakhs) Tenure / Duration Supervisor / Principal Investigator / Co-Supervisor Number of Manpower / Research Fellows Brief Objective
Centre for Distance and Online Education
1.  Understanding Rural Engagement of Village Panchayats for Education: A Study of Sahibzada Ajit Singh Nagar, Punjab
MGNCRE/AR-MI/2021-22dated2022-23/002
Mahatma Gandhi National Council of Rural Education (MGNCRE), Ministry of Education, Government of India, Hyderabad. 300000 9 months Dr. Rajni 2 To understand engagement of Panchayats for education in their villages.
Centre for Human Rights & Duties (U.I.E.A.S.S)
2.  Socio-Psychological Impacts of Drug Addiction on the Wives of the Addicts: A Study of Majha Region in Punjab
13
National Commission for Women, Government of India, New Delhi 773850 9 Months Prof. Namita Gupta 4 Project on“Socio-Psychological Impacts of Drug Addiction on the Wives of the Addicts: A Study of Majha Region in Punjab"
3.  Impact assessment of Crop residue management scheme in Haryana
5921
Director General, Agriculture & Farmers Welfare Department, Haryana, Punchkula. 1320000 6 months Dr. Namita Gupta 8 Impact assessment of Crop residue management scheme in Haryana
Centre for Nanoscience & Nanotechnology (U.I.E.A.S.T.)
4.  Optimization of membrane obtained from organic waste for IOT enabled airpurification device
09/22/907/915
DST Chandigarh 3.50000 1 year Dr Bharat Bajaj 1 Air purifier
5.  Effect of ion implantation on gas sensing capabilities metal oxide nanostuctures
IUACXIII7UFR67316
UGC-IUAC 5.79000 03 Dr. Akash Katoch 1 Gas sensor
6.  Influence of strain on the electronic band strucutre and resistive switching properties of epitaxial oxide heterostrucutres
CRS-301/2019-20/1353
UGC-DAE 6.79300 3 years Prof. Sunil Arora 1 Influence of strain on the electronic band strucutre and resistive switching properties of epitaxial oxide heterostrucutres
7.  Development of Sensing Materials for Exhaled-Breath-Sensor Based on Metal Nanoparticles Functionalized Metal Oxide Nanostructures
DST/INSPIRE/04/2015/001236
DST 14.00000 03 Dr. Akash Katoch 1 Development of gas-sensing materials
Centre for Public Health (U.I.E.A.S.T.)
8.  Impact pf Information, Education, Communication & Youth
3029
Chandigarh State AIDS Control Society, UT, Chandigarh 1.00 6 months Dr. Savita Prashar and Dr. Manoj Kumar 1 The project is proposed to be implemented covering Chandigarh slums as well as urban population. Target Population: Youth of Chandigarh will be the target population of this study. Youth are individuals those aged 18-34 years of age residing in slums and urban settings of Chandigarh.
9.  Development of workplace ergonomics intervention to prevent work-related musculoskeletal disorders in female researchers
18/2021
DST/WOS-B (KIRAN DIVISION) 23.53 3 Years Dr. Neha Bhatia 1 To recognize WMSDs and risk factors, and impact of varying work postures on physical health. To investigate the prevalence and severity of musculoskeletal pain mainly affecting neck, shoulder or low-back region among researchers employed in Panjab University.
Centre for Stem Cell & Tissue Engineering
10.  DBT-BUILDER-Panjab University Interdisciplinary Life Science Programme for Advance Research and Education. BT/INF/22/SP41295/2020
BT/INF/22/SP41295/2020
DBT-BUILDER (Group III) 99998000 60 months Dr. Seemha Rai and Dr. Veena Puri 1 1. To create world-class research facility to perform high-end research in Life Sciences. 2. To train manpower in the upcoming areas of life sciences and for industrial needs. 3. To foster new collaborations with academia and industry. 4. To innovate, invent and disseminate knowledge for the benefit of society.
Department of Anthropology
11.  Forensic Anthropological Provenancing od Human Sleletal remains excavated from a well at Ajnela (Amritsar): Bones, teeth and personal artefacts as identity significances
EMR/2016/006481
DST-SERB 30.58 3 Years Dr. J.S. Sehrawat 1 • To establish the identity/provenance of the victims from the available dental and skeletal material. • To estimate the geographic origin, health and disease conditions, lifetime nutritional and dietary status of the victims from elemental and stable isotope analyses of the teeth and bones. • To extract, quantify and amplify mtDNA from teeth and compare SNP polymorphisms with present day DNA databases of different Indian population groups to opine whether victims were local or non-local to the site. • To identify any traumatic insults or taphonomic damages to the recovered human skeletal and dental remains. • To suggest the minimum or most likely number of individuals based on the available biological and archaeological evidences.
12.  Association of menopausal symptoms and fat distribution with cognitive functions among rural women of Haryana
Nil
DST 2268240 36 Months Dr. Maninder kaur 2 This research project is an attempt to assess cognitive function with respect to different menopausal stages of women. To estimate cognitive function with respect to different menopausal symptoms experienced by perimenopausal and postmenopausal women. To evaluate association of bone mineral density, body fat mass and fat distribution with cognitive function in postmenopausal women
13.  Human Ecology in Northwest India, Biocultural dimensions of health and Disease , Palaeoanthropology and Molecular Anthropology
nil
UGC 94.00 5 Years Prof. Abhik Ghosh and Dr. Maninder Kaur 7 • To collect fossils materials on primates and other mammalian genera to fill gaps in the knowledge. • To reconstruct paleoecology of the region • To collect lithic tools used by the early man in the region • To study DNA unique patterns from the fossil materials on primates • To study the gene flow among the contemporary human populations • To identify individuals, determine paternity estimates relatedness and inferences about whether evolutionary forces are affecting , genetic diversity in natural populations with the help of molecular genetic data • To study Social structure and microsatellite variations in primates
Department of Biochemistry
14.  Development and Evaluation of Potential LXR Modulators Against Sporadic Alzheimer’s Disease
CRG/2022/008902
DST-SERB 1350240 36 months Prof. Rajat Sandhir 1 1. To identify the novel potential LXR modulators by virtual screening and analyzing the structure-function relationship. 2. In vitro evaluation of LXR modulators for agonistic activity in glial-neuron co-culture model system. 3. To study the effect of LXRs modulation on expression of LXRs, NSCs proliferation, differentiation and fate-specification in sAD model. 4. To investigate the effect of LXRs modulation on lipid metabolism, glucose metabolism, lipid raft organization and inflammation in brain hippocampus of sAD model. 5. Evaluating the anti-Alzheimer's like properties of selected lead compound using behavioral and biochemical analysis in animal model of sAD. 6. To investigate the effect of LXR modulation on the status of Wnt/β-catenin signalling pathway in adult hippocampus neurogenesis in a rat model of sAD.
15.  DBT-BUILDER-Panjab University Interdisciplinary Life Science Programme for Advance Research and Education.
BT/INF/22/SP41295/2020
DBT-BUILDER 99998000 60 months Prof. Archana Bhatnagar and Prof. Amarjit Singh Naura 2 1. To create world-class research facility to perform high-end research in Life Sciences. 2. To train manpower in the upcoming areas of life sciences and for industrial needs. 3. To foster new collaborations with academia and industry. 4. To innovate, invent and disseminate knowledge for the benefit of society.
16.  Selection for antimicrobial resistance by antimicrobial production waste.
BT/IN/Indo-UK/AMR-Env/04/IQ/2020-21
DBT 4817120 36 months Dr. Dipti Sareen 1 1. What impact does antimicrobial production waste have on the diversity and abundance of microbial communities? 2. What is the exact chemical composition of antimicrobial production waste? 3.Which components of antimicrobial production waste can select for evolution of resistance to antibiotics?
17.  Investigation of glutamine conjugated organotin compounds as chemotherapeutic agents and their evaluation in colon cancer model systems.
270370/20/EMR-II
CSIR 1500000 36 months Prof. Navneet Agnihotri 0 1. Designing of organotin(IV) compounds using Machine learning-based approaches 2. Synthesis and characterization of glutamine-based organotin(IV) compounds 3. Determination of DNA-binding ability of compounds using computational and biophysical studies. 4. Screening of compounds against colon cancer cell lines. 5.Evaluation of chemotherapeutic potential of selected compounds in experimental model of colon cancer.
18.  Analysis and evaluation of ergosterol and its derivatives as agonists of LXRs and their anticancer potential in colorectal cancer.
5/13/10/2020/NCD-III
ICMR 4759700 36 months Prof. Navneet Agnihotri 0 1. Analysis of the structure-function relationship of LXRs and ergosterol and its derivatives. 2. Determination of antitumor potential of selected LXR agonists in vitro. 3. Determining the antitumor potential of selected LXR agonists in DMH/DSS induced experimental CRC.
19.  Influenza virus-host interplay in viral genome and nucleoprotein (NP) function and identification of host target for therapeutic intervention.
DBT/RLF/Re-entry/05/2015
DBT 10010000 60 months Dr. Dipanjan Dutta 0 1. Characterization of host protein associated with Influence ceirus nucleoprotein. 2. Characterization of host protein associated with ceiral genome. 3. Indentification of viral genome/NP associated cnecial host factors required for ceirus multiplication.
Department of Biophysics
20.  Ameliorating burn wound management with HNP-1 loaded mesoporous silica nanoparticles: A therapeutic approach
SERB/F/9977/2022-2023
DST SERB 34.70 2023-2026 Dr. Simran Preet 1 To develop a potent topical therapeutic arsenal encompassing a woung healing peptide in a non toxic mesh network targeting the wound environment directly.
21.  Development of a novel antibacterial and antibiofilm coating for biomaterial implants and medical devices
17X/60/2022
ICMR 31.30 2022 - 2025 Dr. Avneet Saini 1 • In-silico peptide designing and structural characterization • In-vitro biovalidation of the designed AMPs • Formulation and in-vitro validation of peptide-based biomaterial coating • Establishing the efficacy in in-vivo models
22.  Development and biovalidation of a sustainable Antimicrobial peptide conjugated Collagen Scaffold against infectious bacterial pathogens.
S/1373/29
DST UT 1.20 2022 - 2023 Dr. Avneet Saini 1 1. Extraction and characterization of collagen from the scales of exotic carp 2. Development of Antimicrobial peptide conjugated Fish Collagen scaffold 3. In vitro biovalidation of designed scaffold
23.  Development of a human neutrophil peptide (HNP-1) functionalized antimicrobial catheter against Escheria coli mediated urinary tract infection
OMI/7/2020-ECD-I
ICMR 47.00 2020-2023 Dr. Simran Preet 1 To counter the increasing pathogenesis of E.Coli mediated urinary tract infection post insertion of catheters. Hence, a neutrophil peptide coated catheter development for the purpose of E.Coli eradication in the UTIs.
24.  Aptamer conjugated Teriparatide loaded PLGA/PHBV nanocarriers mediated delivery coners an effective treatment for osteoporosis
00
DHR 54.00 2023-26 Dr. Ravi Pratap Barnwal 1 A novel targeted treatment and it development for osteoporosis patients
25.  Evaluation of a colon targeted nisin loaded nanoformulation for anticancer therapy
09/2022/907-915
DST CHD 1.50 2022- 2023 Dr. Simran Preet 1 To formulate a targeted oral delievery cargo system comprising a novel anticancer peptide
26.  Anticancer therapeutic efficacy of human neutrophil peptide 1 (HNP-1) against 7,12- Dimethylbenzen(a)anthracene (DMBA) induced breast cancer
IF200149
DST INSPIRE 17.00 2021-2026 Dr. Simran Preet 1 To establish the anticancer role of human neutrophil peptide against breast cancer in an in vivo system
27.  In-silico Design and Biovalidation of Novel Peptides/Peptidomimetics: An Advanced Approach Towards Anticancer Regimen
99/20/RUSA/25
RUSA 3.50 1 year Dr. Avneet Saini 1 1. In- silico design of novel anticancer peptides/peptidomimetics 2. Structural characterization 3. In - vitro validation
28.  Targeted co-delivery of nisin coated cisplatin enriched solid lipid nanoparticles against murine skin cancer
2019/IF190190
DST INSPIRE 17.00 2020-2025 Dr. Simran Preet 1 To develop solid lipid nanoparticle of an anticancer peptide for the targeted delivery against skin cancer.
29.  Studies on synergistic potential of human intestinal defensin-5 in conjunction with 5-Fluorouracil against 1,2-dimethylhydrazine dihydrochloride induced colon cancer
2020-7280/PROTEOMICS-BMS
ICMR-Direct SRF 10.22 2021-2023 Dr. Simran Preet 1 To establish strong combinatorial role of HD-5 in conjunction with 5-FU against colon cancer in vivo as well as in vitro.
30.  Diagnostic potential of electrical impedance analyser for bone health detection
letterno2
DST 32.00 2020-23 Prof. M. L. Garg 2 Diagnostic potential of electrical impedance analyser for bone health detection
31.  Serum Metallothionein level determination using a cost-effective impedimetric immunosensor
LetterNo
Seed Fund - FKOL 1.00 2020-21 Prof. M. L. Garg 3 Serum Metallothionein level determination using a cost-effective impedimetric immunosensor
32.  Insilico identification and experimental validation of novel chemical chaperones for preventing amyloid aggregations and rescue cognitive behavior in Alzheimer’s disease rat model
DST/CSRI/2018/70
DST 48.00 2020-2023 Dr.Tanzeer Kaur 1 1. Identification of lead chaperones in silico. 2. Chemical Synthesis of lead chaperones 3. In vitro activity studies 4. In vivo activity studies
33.  Development of a novel nisin loaded organogel system: A topical therapeutic approach against skin cancer
EEQ/2017/000540
DST SERB 43.00 2017- 2020 Dr. Simran Preet 1 To develop a novel topical dual cargo delivery sytem encompassing both peptide and chemodrug against skin cancer
34.  Evaluation of therapeutic potential of human intestinal alpha defensin 5 against colorectal cancer
YSS/2015/001275
DST SERB 30.50 2015- 2018 Dr. Simran Preet 1 To establish HD-5 as a strong anticolon cancer peptide
Department of Biotechnology
35.  Tissue culture studies on important medicinal plants
NA
Nanotech Chemical Brothers under CSR 30 3 years Dr Kashmir Singh 1 Development of tissue culture protocol for selected medicinal Plants and Scale-up technology for enhancement of metabolites
36.  Dissecting G-protein signaling pathway in Arabidopsis under salt stress
DST/WOS-A/LS-284/2019
DST-WOS 3279312 3 years Dr. Monika Bhuria 0 Comparative Proteome analysis of three G proteins mutants under salt stress in Arabidopsis and identification and characterization of effector proteins
37.  The Study of Technology Transfer Centers to Increase Commercialization of Innovation
3000104302
United Nations industrial development organization (UNIDO) 3152073 9 months Dr Kashmir Singh 2 the study of Technology Transfer Centres to increase commercialization of innovation under the project ‘’ for Low Carbon Technology Deployment
38.  Genome Editing Mediated Nutritional Improvement of Potato (Solanum tuberosum L.)"
BT/PR38402/GET/119/308/2020
DBT 11800000 3 years Dr Kashmir Singh 1 Identification and characterization of St16DOX, StAS, and StIRO3 from potato genome, gene editing / silencing, transformation, metabolic profiling of glycoalkaloids
39.  To study the crosstalk between long non-coding RNAs and MYB transcription factors for enhancement of drought tolerance in Brassica sp
EEQ/2021/000036
SERB 4602042 3 years Dr Kashmir Singh 1 In silico analysis-mediated re-mining of endogenous target mimics (eTMs) from the identified Brassica juncea drought-responsive lncRNAs and characterization
40.  Mechanistic insights into redox dependent autophosphorylation and anti-oxidant function of truncated haemoglobin, o, in Mycobacterium tuberculosis
CRG/2021/006823
DST-SERB 37.89 3 years Dr. Kanak Lata Dikshit 1 Studies on in vivo status of trHBO in Mtb. Transcript analysis, the glbO gene, SigH regulated genes and characterization.
41.  Rapid visual Identification of Acinetobacter baumannii and its carbapenem resistance determinants using gold nanoparticles-based biosensor
OMI/12/2020-ECD-I
ICMR 47.65 3 years Dr. Neena Capalash 2 Identification and development of A.baumannii specific DNA oligo-sequences, evaluation of role in carbapenem resistant strains and developing as DNA probe
42.  Exploring the resistance potential of pseudo R-genes to evoke fungal resistance in Vitis vinifera (Grapevine)
CRG/2020/000762
SERB 5847092 3 years Dr Kashmir Singh 1 Genome-wide identification of pseudo R-genes in Vitis vinifera, stability studies, functional characterization and expression analysis in plants
Department of Botany
43.  Engineering Iron biofortified potato with low toxic glycoalkaloid content through CRISPR-Cas mediated genome editing
SPARC/2019-2020/P2355/SL
Scheme for Promotion of Academic and Research Collaboration 4549040 2 years Dr. Kashmir Singh 3 Engineering Iron biofortified potato with low toxic glycoalkaloid content through CRISPR-Cas mediated genome editing
44.  Genome Editing Mediated Nutritional Improvement of Potato (Solanum tuberosum L.)
BT/PR38402/GET/119/308/2020
Ministry of Science & Technology, Department of Biotechnology, GOI 11716080 3 years Dr. Kashmir Singh 3 Genome Editing Mediated Nutritional Improvement of Potato (Solanum tuberosum L.)
45.  Functional characterization of TaMSL5-D gene of bread wheat”
NA
Science and Engineering Research Board (SERB) 61.95 3 years Dr. S.K. Upadhyay 1 Functional characterization of TaMSL5-D gene of bread wheat”
46.  Ecological assessment--- -Sukhna Wetland Ecosystem
58/GP
DST, Chandigarh 100000 2 years Dr. A.N. Singh 1 Ecological restoration of Sukhna
47.  Characterisation of chickpea germplasm resource to accelerate genomics assisted crop improvement
Bt/ag/Network/Chickpea/2019-20
DBT, New Delhi 10000000 5 years Prof. Harsh Nayyar 1 Characterisation of chickpea germplasm resource to accelerate genomics assisted crop improvement
Department of Chemistry
48.  Design and Synthesis of New Amphiphatic Cyclopeptides, Study of their Antimicrobial Activity and Antibiotic Synergy
SUR/2022/004226
DST-SERB 2992000 3 years Dr. Deepak B. Salunke 1 To synthesize a library of novel bile acid based cyclopeptides comprising valine, lysine, glutamine, glutamate and serine. • In vitro antimicrobial study with gram positive (S. aureus ATC 29213), gram negative (Escherichia coli ATCC 25922, Pseudomonas aeruginosa) and anti-fungal strain (Candida albicans). • Fluorometric assessment of selective permeabilization of microbial membranes will be investigated using 1-N phenylnaphthylamine and/or 3,3-diethylthiadicarbocyanine iodide probes to see the membrane-permeabilization behavior of the synthesized compounds. • Synergistic effect of synthesized analogs in combination with other antibiotics (cefotaxime, amikacin, ciprofloxacin, and vancomycin). • To determine the activity of the compounds against the drug-resistant clinical isolates of S. aureus 1704, E. coli 4052, and C. auris.
49.  Project titled "Development of NIR Emitting Peptide Conjugated Metallic Nanoclusters for Effective Photothermal Therapy
CRG/2022/006638
DST-SERB 3692000 3 years Dr. Rohit Kumar Sharma 1 1: Synthesis and characterization of metallic nanoclusters (MNCs) as photothermal agents (PTA) in NIR domain Objective 2: Synthesis and characterization of tumor targeting peptides (TTPs) to enhance the selectivity of photothermal agents (PTAs) Objective 3: Conjugation of highly specific tumor targeting peptides (TTPs) to PTAs as an efficient and selective system for improved PTT
50.  Development of new lipidated small molecules as potential vaccine adjuvants
STRE/RP/147/e-2873/22-23/Sanc/09/202
DST-UT 200000 1 year Dr. Deepak B. Salunke 0 The project will comprise of following segments: 1. To optimise the synthesis of hybrid structures comprising TLR7/8 agonistic imidazoquinolines linked to TLR2 agonistic lipopeptides: Two hybrid compounds will be synthesized as described in the work plan. 2. Purification and characterization of the synthesized hybrid molecules. 3. Screening of the TLR7/8 and TLR2 agonistic activity as well as cytotoxicity of the synthesized hybrid molecules.
51.  Development of peptide-based infection imaging agents
58/14/14/2022-BRNS/37060
BRNS 4087600 3 years Dr. Rohit Kumar Sharma 1 1. To Synthesize novel peptides for development of infection imaging agents 2. To Synthesize novel AMP conjugates for radio-labelling to be used for in vitro evaluation of new infection imaging agents.
52.  Fabrication of polymer dots from multicomponent tandem polymer receptors for sensing applications
SPG/2021/002995-G
DST-SERB 2884200 3 years Prof. Navneet Kaur 0 Development and characterization of variedly substituted monomeric and polymeric receptors based on Pyrimidine derivatives by multicomponent single pot reactions. Evaluation and sensing activity of developed sensor systems for detection of biologically important analytes.
53.  Fabrication of ultrasensitive smart kit for detection of toxic lead traces in water, food and soil samples
306/RUSA/2022
RUSA 500000 2 years Dr. Rohit Kumar Sharma 1 1: Optimizations for the sensitive, selective and rapid detection of lead ions by developing aptasensor using cationic peptide and plasmonic gold nanoparticles Objective 2: Fabrication of portable detction kit using the developed aptasensor for detection of Pb2+ ions in various water, food and soil samples Objective 3. Validation of Pb2+ ions in real samples using the designed kit and quantitative analysis using electronic/smartphone
54.  Biocompatible metallosomes: fabrication, characterization and their interactional behavior with biomolecules
CRS/2021-22/03/543
UGC-DAE CSR 243240 3 years Dr. Gurpreet Kaur Department of Chemistry PU 0 (i) To synthesize metallosurfactants based metallosomes with varying metal ions and surfactants. (ii) Systematic characterization of prepared metallosomes. (iii) To explore these metallosomes for encapsulation of dyes. (iv) To study the interaction of metallosomes with biomolecules i.e. Protein, DNA, RNA etc.
55.  Nanodelivery and evaluation of adjuvant effect of synthetic TLR4 and TLR7 agonists combination in chicken
CRG/2021/005467
DST-SERB 6218400 3 years Dr. Saravanan Ramakrishnan Senior Scientist IVRI Bareilly 1 The aim of project is to design and synthesize novel TLR4 and TLR7 agonists and adjuvantic effect these agonists will be explored for malaria and influenza. The delivery systems such as Lipid carriers and Nano emulsion will be fabricated to encapsulate these agonists.
56.  COPPER PSEUDOATRANES: SYNTHESIS OF MONO- AND BIMETALLIC CAGES WITH RIGID AND ASYMMETRIC SKELETONS FOR THEIR POTENTIAL APPLICATIONS
013075/21/EMRII
CSIR (HRDG) 1400000 3 years Dr. Varinder Kaur 0 1. To synthesize tripodal ligands capable of binding single and multiple metal ions. 2. To synthesize homometallic and heterobimetallic [4.4.3.01,5]tridecane and [4.4.4.01,6]tetradecane cages of copper in pure form. 3. To investigate the structural aspects of the synthesized complexes. 4. To investigate the spectroscopic aspects of the complexes. 5. To apply the synthesized complexes in sensing or catalysis applications.
57.  SYNTHESIS OF MONO AND BIMETALLIC PSEUDOSTANNATRANE CAGES WITH RIGID AND ASYMMETRIC SKELETONS FOR THEIR POTENTIAL APPLICATIONS
SPG/2021/000455
SERB-POWER, India 2914164 3 years Dr. Varinder Kaur 1 1. To synthesize and characterize polydentate tripodal ligating systems 2. To synthesize and characterize mono- and heterobimetallic pseudostannatranes. 3. To investigate the spectroscopic and structural features of pseudostannatranes. 4. To investigate the potential applications of pseudostannatranes.
58.  Novel and pliable anthraquinone derivatives for chemo sensing applications
02/0446/21/EMR-II
CSIR, New Delhi 1400000 3 years Dr. Navneet Kaur 0 To synthesize and characterize tailor made anthraquinone based sensors for their chemo sensing applications.
59.  INVESTIGATION OF GLUTAMINE CONJUGATED ORGANOTIN COMPOUNDS AS CHEMO-THERAPEUTIC AGENTS AND THEIR EVALUATION IN COLON CANCER MODEL SYSTEMS
27/0370/20/EMR-II
CSIR-HRDG 1500000 3 years Dr. Navneet Agnihotri 0 1. Synthesis and characterisation of glutamine-based novel organotin derivatives with varying hydrocarbyl groups 2. Selection of potent organotin compounds based on their DNA binding ability 3. Biological characterisation of selected organotin compounds; (i) In vitro studies using colon cancer cell lines (ii) In vivo studies in an animal model of colon carcinoma
60.  Anti-leukemia Peptide Conjugated Quantum dots based targeted formulations as new-age theranostics
SPARC/2018-2019/33/SL/IN/
SPARC-MHRD 3829986 4 years Dr. Rohit Kumar Sharma 0 Anti-leukemia Peptide Conjugated Quantum dots based targeted formulations as new-age theranostics
61.  Development of Synthetic TLR2, TLR7/8 and Mincle Agonists for Use as Part of a Combination Adjuvant in Tuberculosis Vaccines
SPARC/2018-2019/P386/SL
SPARC-MHRD 4440000 5 years Dr. Deepak B. Salunke 1 The specific aims of this proposal are: 1. To use available Structure Activity Relationship (SAR) information together with in silico high throughput screening to identify and design novel TLR2, TLR7/8 and Mincle ligands 2. To design methods to chemically synthesize these novel agonists and their self-conjugation with antigen as well as with the AdVax adjuvant and test the specificity of these ligands using TLR2, TLR7/8 and Mincle expressing reporter cell lines 3. To test the capacity of these agonists alone or in combination in murine models to enhance protection of a TB vaccine platform against M. tb infection.
Department of Defence and National Security Studies
62.  External Aggression and Infrastructure Development along India China Border: Issues and Challenges with special reference to Local Population
02137202223
ICSSR 1418920 24 months Dr. Jaskaran Singh Waraich 0 To delineate the instances of external aggression from China along the India- China border in terms of the issues which triggered these, the response from either side and the role and perception of local population. • To map and document the extent of infrastructural development along the border. • To examine the impact of such aggressive and developmental impulses on the border landscapes and in the lives and perceptions of the people. • To determine the perception and response of the local population residing in the vicinity of the borders to external aggressions and infrastructure development • To determine the implications of the external aggressions and infrastructure development for national security
Department of Environment Studies
63.  Community Environmental Empowerment Program (CEEP)
Q-16017/15/2021-CPA
MOEFCC, GOVT. OF INDIA 19121520 3 YEARS Dr. Suman Mor PU CHANDIGARH 8 INVOLVEMENT OF COMMUNITIES TO IMPART THE KNOWLEDGE AND RAISE THEIR AWARENESS FOR BETTER UNDERSTANDING AND ENSURING NECESSARY MEASURES AGAINST THE INCREASING LEVEL OF AIR POLLUTION DEVELOP INFORMATION, EDUCATION AND COMMUNICATION (IEC) MATERIAL AND STRATEGY TO EDUCATE STUDENT AND COMMUNITY
64.  Preparation of State Specific Action Plan (SSAP), Chandigarh
CE/MC/385
NATIONAL WATER MISSION 2703380 1 YEAR DR. NAVAL KISHORE 2 SPECIFIC ACTION PLAN FOR CITY CHANDIGARH
Department of Geography
65.  External Aggression and Infrastructure Development along India China Border: Issues and Challenges with Special Reference to Local Population
02/137/2022-23/ICSSR/RP/MJ/GEN
ICSSR 14.18 2 Years Dr. Jaskaran Singh Waraich 2 The study will be guided by the following objectives: *To delineate the instances of external aggression from China along with India-China Border in terms of the issues which triggered these, the response from either side and the role and perception of local population. *To map and document the extent of infrastructural development along with border. *To examine the impact of such aggressive and developmental impulses on the border landscapes and in the lives and perceptions of the people. *To determine the perception and response of the local population residing in the vicinity of the border to external aggression and infrastructure development. * To determine the implications of the external aggression and infrastructure development for national security.
66.  Tribal Dilemma in the Himalayan Mountains: Dams, Disasters and Development in the Lahaul Valley of Himachal Pradesh
02/105/GN/2021-22/ICSSR/RP/MJ
ICSSR 10.50 2 Years Dr. Vishwa Bandhu Singh 2 The study aims at analyzing the links between disasters and hydro power development in the valley in light of climate change.
Department of Geology
67.  Landslide Forewarning System for Manikaran, Himachal Pradesh, India.
NGP/LS/MaheshThakur/TPN34319/2019
Department of Science and Technology, Govt. of India 56.7 3 years Dr. Mahesh Thakur 1 Risk assessment using artificial intelligence for monitoring landslides. Installation of Landslide Early warning system at Manikaran
68.  Integrated palaeontology, biostratigraphy and sedimentology of the Cambrian successions of the Nelang Valley (Garhwal Himalaya) and Kali Valley (Kumaun Himalaya), Uttrakhand: its regional and global correlation
24/0365/20/EMR-II
CSIR 9 2021-2024 B.P.Singh 0 Biostratigraphic zonation and sedimentological evolution of the Cambrian successions in the Nelang (Garhwal) and the Kali valleys (Kumaun) and its regional and global correlation and palaeogeographic reconstruction based on paleobiogeograhic analysis
69.  Assessment of Rare Earth Elements (REEs) in other economic resources in Coal and Non Coal Strata and Characterization of Acid Mines Dranage and its pollution control form the North Eastern region (NER) Coalfield, India
EE-51/479
MoC 361 2 years & 6 months Dr. Debabrata Das 2 Economic potentiality of critical mineral from secondary sources (coal & its byproducts) and develop technique for controlling acid mine drainage.
70.  Collaborative Research: A Chronology and Ecological Context of Primate and Mammalian Evolution
1945736
National Science Foundation , USA 185 4 years Chris Gibery 0 To Search for Early Hominoids in the Ramnagar Siwaliks and establish a chronological framework
71.  Subsistence and symbolism in prehistoric India: Understanding environmental contexts in relation to Homo sapiens dispersals and adaptations
2019/651
MHRD Govt. of India 99.39 5 years Prof. Parth Chauhan 0 To set a model for multidisciplinary collaborative research in Indian prehistory (archaeology, palynology, paleontology, geology)
72.  Rodent-based biochronology and palaeoecology of the Neogene Terrestrial sequences of Kutch and Kathiawar, Gujarat & HR
R/2018/000063
SERB, Govt. of India 52.43 5 years Prof. Rajeev Patnaik 2 To search for small mammals from the Neogene terrestrial deposits exposed in Kutch and Kathiawar, Gujarat and to date these sediments using rodent biochronology.
73.  Active Fault, Paleoseismic and crustal deformation in NW and Central Himalaya, India: An integrated approach towards Seismic Hazard Assessment
MoES/1/271/AFM/2015
Ministry of Earth Sciences, Govt. of India 92 7 years Dr. Mahesh Thakur 0 Active fault mapping and Paleoseismology
Department of Mathematics
74.  DST-FIST Level-II
SR/FST/MS2/2019/43C
Department of Science and Technology 8700000 5 Years Chairperson Department of Mathematics 0 DST-FIST Level-II
75.  NASI Senior Scientist Fellowship 2022
NASI/300/12/2021
The National Academy of Sciences NASI 470000 2 years Prof. Madu Raka 0 The National Academy of Sciences NASI Fellowship
Department of Microbial Biotechnology
76.  Design and synthesis of new amphipathic cyclopeptides, study of their antimicrobial activity and antibiotic synergy
SUR/2022/004226
SERB - SURE 29 3 years Dr. Deepak Salunke 1 To design new amphipathic cyclopeptides and evaluate their antimicrobial activity against clinically-relevant microbes.
77.  Development and evaluation of peptide-derived moieties for antimicrobial activity, particularly antifungal activity against pathogenic Zygomycetes
67/2/2020-DDI/BMS
Indian Council of Medical Research 22 3 years Dr. Rachna Singh 1 The project aims to develop and evaluate peptide-derived moieties for antimicrobial activity, particularly antifungal activity against pathogenic Zygomycetes
78.  E-YUVA
BIRAC/SPED/EYUVA2021
BIRAC New Delhi 236.5 03 Years Dr. Rohit Sharma 18 Entrepreneurship Development and pre-incubation
79.  Purification of Protein from Bacteria 201808004
201808004
RIL Mumbai 50.05 3 years Dr. Rohit Sharma 2 Research Project
80.  BioNest
BT/BIRAC/BI-PU/2017
BIRAC New Delhi 411 7 years Dr. Rohit Sharma 4 Entrepreneurship Development and promotion of Start-up ecosystem
Department of Microbiology
81.  To study and compare the sewage treatment at various STPs in Chandigarh and evaluation of tertiary treated water at UGRs and supply chain.
147/2873/22-23/09/202
DST-UT 2.50 1 Year Dr. Naveen Gupta 1 I. Collection of treated sewage water from various STPs and tertiary treated water from UGRs and supply chain in Chandigarh II. Assessment of BOD, COD of the water samples. III. Monitoring of MPN count and presence of various pathogenic organisms. IV. Assessment of other parameters including presence of heavy metals, dissolved solids, hardness etc. V. Monitoring the intensity and frequency of bad odor in tertiary treated water at various points
82.  Deciphering the microbiome landscape of native and migrated "Pangwala" tribal population of India : A pilot scale tribal microbiome Initiative.
12020/13/2018
HRD Scheme of the Department of Health Research 28.26 3 years Mr. Khem Raj 1 I. Sample collection, transportation and preservation II. DNA extraction, PCR amplification of 16S rDNA and amplicon sequencing. III. Sequence processing and bioinformatics analysis of microbiome composition.
Department of Political Science
83.  Prospering Girls in a Gender Focus Development Agenda: A Multi- dimensional Study of the Sukanya Samriddhi Yojana in Four States of India
260/CRP-2023-519/SSY/SCD
Indian Council of Social Science Research (Ministry of Education) JNU Institutional Area, Aruna Asaf Ali Marg New Delhi 1500000 6 months Dr. K. M. Baharul Islam 1 Women play an integral part in society; without their progress, the overall progress of society comes to a halt. Societies in which women see consistent growth have been known to prosper themselves. It is through the empowerment of women that societies can ensure their growth as well.
84.  Short-term Empirical Research Project (Collaborative/Individual) entitled “Prospering Girls in a Gender Focus Development Agenda: A Multi- dimensional Study of the Sukanya Samriddhi Yojana in Four States of India”
260/CRP-2023-519/SSY/SCD
Indian Council of Social Science Research 1500000 6 months Dr. K. M. Baharul Islam 4 Sanction of Short-term Empirical Research Project (Collaborative/Individual) entitled “Prospering Girls in a Gender Focus Development Agenda: A Multi- dimensional Study of the Sukanya Samriddhi Yojana in Four States of India” to Dr. K. M. Baharul Islam, Indian Institute of Management Kashipur.
Department of Public Administration
85.  Addressing Poverty and Vulnerability through Deendayal Antyodaya Yojana National Rural Livelihood Mission (DAY-NRLM) - An Analytical Study of Haryana and Chandigarh
PR-MJRP/2021-22/MGNCRE
Mahatma Gandhi National Council of Rural Education, Hyderabad 550000 17 Months Dr. Navreet 2 Addressing Poverty and Vulnerability through Deendayal Antyodaya Yojana National Rural Livelihood Mission (DAY-NRLM) - An Analytical Study of Haryana and Chandigarh
86.  Impact of Various In-Service teachers' training under SSA on learning outcomes: A Case Study of Select Districts of PunjabImpact of Various In-Service teachers' training under SSA on learning outcomes: A Case Study of Select Districts of Punjab
196/SDP/SCERT/2019
SCERT, Punjab 350000 12 months Dr. Bharati Garg 0 Impact of Various In-Service teachers' training under SSA on learning outcomes: A Case Study of Select Districts of Punjab
Department of Zoology
87.  Chemoattenuated blood stage Plasmodium vaccine
BIRAC/01760
BIRAC, DBT 50.00 1 year 6 months (Nov 2022- May 2024) Prof. Sukhbir Kaur 1 Malaria is an infectious disease affecting RBCs. Till now there has been no effective malaria vaccine. Chemoattenuation provides a facile technology in generation of immunity.
88.  To evaluate the antileishmanial and antiplasmodial efficacy of novel nosodes of Leishmania donovani and Plasmodium falciparum in combination with standard antileishmanial and antimalarial drugs respectively against leishmaniasis and malaria.
17-13/2022-23/CCRH/TECH/COLL/PU/5565
CCRH, New Delhi 77.56 3 years (2022-2025) Prof. Sukhbir Kaur 3 The standard drugs used for treating malaria and leishmaniasis have many side effects and are toxic. So in this project we will use a combination of nosodes prepared from parasites along with low doses of standard antimalarial/antileishmanial drugs, which might help to reduce the dose of the standard drug, thereby reducing toxicity. In addition the nosodes have an immunomodulatory effect which might further help in providing protection from these deadly diseases. Malaria is an epidemic infectious disease. Chemoattenuated vaccine provides a persistent and protective immunity against Plasmodium. The aim of this project is to evaluate effect of route of administration and strain transcending potential of chemoattenuated formulation in murine infection model. Malaria is an infectious disease affecting RBCs. Till now there has been no effective malaria vaccine. Chemoattenuation provides a facile technology in generation of immunity. The aim of this project is to evaluate various parasitological and immunological determinants required for the generation of immunity.
89.  Evaluation of mode of immunization and strain transcending immune potential of chemoattenuated blood stage Plasmodium vaccine
00
START UP & Innovation Project under RUSA, PU 10.00 2 years (2022-2024) Prof. Sukhbir Kaur 1 Malaria is an epidemic infectious disease. Chemoattenuated vaccine provides a persistent and protective immunity against Plasmodium. The aim of this project is to evaluate effect of route of administration and strain transcending potential of chemoattenuated formulation in murine infection model.
90.  Screening Bee stings for antimicrobials against Bacteremia by Streptococcus pneumoniae in Children
BT/PR33040/MED/97/465/2019
DBT, New Delhi 6480000 3 years (2021-2024) Dr. Srinivas Kiran Ambatipudi 0 1. Identifying Antimicrobial activity of bee sting extract on Streptococcus Penumoniaein vitro. 2. Bee extract purification, in vitro antimicrobial assay and characterization of active conponents. 3. Cytotoxicity assay using active compounds 4. Cytotoxicity and antibacterial efficacyof bee stingextract using murine model
91.  Diversity and molecular phylogeny of Myxozoan parasites infecting freshwater fishes in Punjab and their biological effects
CRG/2020/004917
DST-SERB 28.61 3 years (2020-2023) Dr. Harpreet Kaur Bimbra 1 To document the diversity of myxozoan parasites infecting freshwater fishes in natural and cultured habitat in Punjab using basic taxonomic approaches and 18SSU and 28LSU rDNA. To identify myxozoan infections in the alternate host (harboring actinospore stage) and myxospore stages in the water bodies/ tissue sample of the host using qPCR and eDNA Approaches. To study the phylogenetic analysis of myxozoan parasites using Next generation sequencing. To study the biological effects of myxozoan parasites on the fish host using various biochemical, immunological and histopathological methods. To generates a baseline data on myxozoan diseases and their risk assessment in cultured fishes.
Institute of Forensic Science & Criminology
92.  Development of Effective Scientific Method for Identification of Trace Evidence in Crimes against Women
EMR
Ministry of Home Affairs 4765600 24 Dr. Vishal Sharma 1 To develop analytical methods for the identification of trace Evidence in Crimes against Women Use of machine learning and chemometric methods for the spectral database.
University Institute of Pharmaceutical Sciences
93.  Aptamer conjugated Teriparatide loaded PLGA/PHBV nanocarriers mediated delivery coners an effective treatment for osteoporosis
2023
DHR 60.00 36 Prof. Sanjay K Bhadada 1 A novel targeted treatment and it development for osteoporosis patients
94.  VirusInspired peptide design of monomeric pseudo-alpha helix for the recognition of its RNA targets
2023
CSIR 45.00 36 Dr Ravi Pratap Barnwal 1 Development of pseudo helix peptide for different RNAs.
95.  A fluorescent cyclic peptide conjugated amphipathic-D diastereomers nanotherapeutics for an early detection and treatment of prostate cancer
CRG/2022/000628
DST-SCIENCE & ENGINEERING RESEARCH BOARD (SERB) 60.00 Three years Dr Gurpal Singh 1 This project is particularly focusing on early stage detection and treatment of prostate cancer
96.  Development of new chemo-immunotherapy approach for colorectal cancer
CRG/2022/003884
SERB-CRG 59.00 36 Professor Kanwaljit Chopra 1 Despite advances in cancer therapy employing chemo, immuno and radiotherapy, nonsignificant reduction in mortality and relapse rate have remained a major challenge. Very recently, a promising approach of chemo-immunotherapy is being explored wherein the potential synergism of two gating strategies will be harnessed to achieve a much robust therapeutic response. The main objective of our study is to elucidate the role of indigenously synthesized novel toll like receptor (TLR)7 / 8 agonists in combination with traditional chemotherapeutic agents in in-vitro and in-vivo models of colorectal cancer along-with biochemical, molecular, genetic and histopathological biomarkers elucidation. The findings will substantiate the role of TLR-7 and 8 as novel targets for chemo-immunotherapy. These compounds can be further translated in to the clinics.
97.  Aptamer conjugated QDs based fluorescence technique for rapid detection of Lead in drinking ground and surface water
2022
DST-UT 2.00 12 Dr Ravi Pratap Barnwal 1 Rapid method development for the detection of Lead
98.  Development of gold nanoparticles based lateral flow immunoassay for rapid and early detection of novel biomarker microRNA-204 in type 1 diabetes (T1D)
2022
ICMR 55.50 36 Dr Ravi Pratap Barnwal 1 Lateral flow technology will be developed for early stage detection of type 1 diabetes
99.  API and Intermediate Synthesis
2022
Valence Labs Pvt Ltd. 111.00 60 Professor Ranju Bansal 3 The objective of the project is development of low cost improved process of some selected APIs and their key intermediates by adopting new synthetic routes.
100.  SalFluSENSOR: Fluorescence based nanobiosensor design for rapid and specific detection of Salmonella and Influenza
2021
DHR 30.00 36 Dr Ravi Pratap Barnwal 1 Fluorescence based nanobiosensor will be designed for early stage detection of salmonella and influenza pathogens
101.  Development of nanoinhibitor against CssA RNA thermometer from Neisseria meningitis
2022
ICMR 10.00 24 Dr Ravi Pratap Barnwal 1 To develop inhibitors for Neisseria meningitis
102.  Identification and Characterization of Downstream Effector Proteins for Gao, the Major Neural G protein in Brain Tissue
2020
DBT 61.00 36 Dr Santosh Kumar 1 Here identification and characterization of downstream effector proteins for Gao will be explored
103.  Development and evaluation of fish oil - probiotic supplemented composite dressing for chronic wounds
CRG/2019/002768
DST-SCIENCE & ENGINEERING RESEARCH BOARD (SERB) 44.44 36 Professor Indu Pal Kaur 1 Development and evaluation of fish oil - probiotic supplemented composite dressing for chronic wounds
104.  Biohybrid antisense PNA-graphene QD stargeting bcl-2 gene for cancer theranostic
BMS/Adhoc/15/2020-21
ICMR 38.00 3 year 5 months Dr Gurpal Singh 1 A photosensor will be developed for rapid deduction of early stage breast cancer and their treatment
105.  Liposomal Technology Platform
61/UIPS/OPK
BDH Industries Pvt Ltd, Mumbai 4.93 36 Professor O.P. Katare 1 Liposomal Technology Platform
 
 

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